The ESMO/SIOG Cancer in the Elderly Working Group pragmatic strategies for clinical trial designs and endpoints in older adults with cancer
We recommend investing in geriatric oncology clinical trial designs that incorporate traditional survival endpoints, as well as prioritise outcome measures affecting quality of life and function in line with the patient goals and preferences.
Authors
- N.M.L. Battisti
- A.R.A. Mislang
- L. Dal Lago
- M. Frelaut
- F. Gomes
- L. Cooper
- S. Pilleron
- W.K. Soo
- N.R. Neuendorff
- E. Brain
- S. Rostoft
- M. Puts
- S. O’Hanlon
- B. Canin
- A. O’Donovan
- C. Baldini
- L. Biganzoli
- M. Bringuier
- F. Canoui-Poitrine
- R. Kanesvaran
- K.-L. Cheung
- H. Wildiers
- D. Papamichael
Institutions
- University College Dublin (IE)
- Oslo University Hospital (NO)
- Royal Marsden NHS Foundation Trust (GB)
- University of Nottingham (GB)
- Inserm (FR)
- Flinders University (AU)
- University of Oslo (NO)
- Université Paris-Est Créteil (FR)
- Trinity College (CA)
- Trinity College Dublin (IE)
- Université Paris-Saclay (FR)
- Rabin Medical Center (IL)
- Institut Gustave Roussy (FR)
- Princess Margaret Cancer Centre (CA)
- Flinders Medical Centre (AU)
- Universitätsklinik Marien Hospital Herne (DE)
- Assistance Publique – Hôpitaux de Paris (FR)
- Eastern Health (AU)
- Luxembourg Institute of Health (LU)
- Mater Private Hospital (AU)
- The Christie NHS Foundation Trust (GB)
- National Cancer Centre Singapore (SG)
- Centre Hospitalier Interrégional Edith Cavell (BE)
- Community Options (United States) (US)
- Bank of Cyprus Oncology Center (CY)
- Hospital of Prato (IT)
- Institut Curie (FR)
- KU Leuven (BE)
Publication Details
- Journal
- ESMO Open
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1016/j.esmoop.2025.105940
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00