Nationwide analysis on sex differences in diagnosis, treatment and survival of rectal cancer

Sex-based differences exist in rectal cancer presentation and outcome. Women are more likely to present a more advanced T-stage. Despite this, women have a better overall survival after surgical treatment. In contrast, men and women undergoing treatment for asymptomatic rectal cancer have comparable outcomes.

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Publication Details

Journal
Biology of Sex Differences
Published
2026-02-22
DOI
https://doi.org/10.1186/s13293-026-00863-3
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Nationwide analysis on sex differences in diagnosis, treatment and survival of rectal cancer

J. M. van Rees, D. M. Mens, R. R. J. Coebergh van den Braak, V. M. T. van Verschuer et al.
Biology of Sex Differences
Colorectal Cancer Surgical Treatments
article

Nationwide analysis on sex differences in diagnosis, treatment and survival of rectal cancer

J. M. van Rees, D. M. Mens, R. R. J. Coebergh van den Braak, V. M. T. van Verschuer, D. E. Hilling, C. Verhoef
article en

Abstract

Sex-based differences exist in rectal cancer presentation and outcome. Women are more likely to present a more advanced T-stage. Despite this, women have a better overall survival after surgical treatment. In contrast, men and women undergoing treatment for asymptomatic rectal cancer have comparable outcomes.

Biology of Sex DifferencesVol. 17(1)
Radboud University Nijmegen (NL), Catharina Ziekenhuis (NL), Erasmus MC Cancer Institute (NL), Rotterdam University of Applied Sciences (NL)
Openalex Percentile: Top 45%
Colorectal Cancer Surgical Treatments
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