Platelet and Doppler ultrasound signatures of histological fibrosis in chronic liver disease: a correlation study based on Ishak staging
PLT and selected Doppler ultrasound parameters change in parallel with histological fibrosis severity, reflecting the progressive development of portal hypertension and vascular remodeling. These findings support a combined, trend-based interpretation of PLT and Doppler ultrasound markers as accessible, non-invasive indicators of advanced liver disease, rather than as stand-alone diagnostic tools.
Authors
- Marco Musmeci
- Livia Masi
- Carla Serra (ORCID: https://orcid.org/0000-0001-5555-0745)
- Andrea Boccatonda (ORCID: https://orcid.org/0000-0001-9303-7790)
- Sofia Maria Bakken (ORCID: https://orcid.org/0009-0001-0860-1324)
- Maria Chiara Garlisi
- Alice Brighenti
Institutions
- IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
Publication Details
- Journal
- Journal of Ultrasound
- Published
- 2026-02-22
- DOI
- https://doi.org/10.1007/s40477-026-01126-y
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università di Bologna
- Samsung