Real-world evaluation of the transition between originator and follow-on glatiramer acetate in people with multiple sclerosis: the “GA transition” study

Switching from originator GA to CO did not influence clinical outcomes or safety. These findings support the therapeutic equivalence of the two formulations in real-world clinical practice, by supporting previous evidence from randomized trials.

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Publication Details

Journal
Multiple Sclerosis and Related Disorders
Published
2026-02-21
DOI
https://doi.org/10.1016/j.msard.2026.107088
Primary Topic
Multiple Sclerosis Research Studies
Type
article
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article

Real-world evaluation of the transition between originator and follow-on glatiramer acetate in people with multiple sclerosis: the “GA transition” study

Cinzia Cordioli, P. Cavalla, Alessio Carbone, Beatrice Giovannini et al.
Multiple Sclerosis and Related Disorders
Multiple Sclerosis Research Studies
article

Real-world evaluation of the transition between originator and follow-on glatiramer acetate in people with multiple sclerosis: the “GA transition” study

Cinzia Cordioli, P. Cavalla, Alessio Carbone, Beatrice Giovannini, Alice Laroni, Giacomo Lus, Mattia Pozzato, Sarah Rasia, Pietro Annovazzi, Elisabetta Signoriello, Maria Pia Sormani, Sara La Gioia, Alessia Di Sapio, Chiara Zecca, Irene Schiavetti, Valentina Torri Clerici
article en

Abstract

Switching from originator GA to CO did not influence clinical outcomes or safety. These findings support the therapeutic equivalence of the two formulations in real-world clinical practice, by supporting previous evidence from randomized trials.

Multiple Sclerosis and Related DisordersVol. 109
University of Pisa (IT), Associazione Italiana Sclerosi Multipla (IT), Laboratory for Biomedical Neurosciences (CH), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Ospedale Papa Giovanni XXIII (IT), Krankenhaus Meran (IT), University of Campania "Luigi Vanvitelli" (IT), Ospedale San Luigi Gonzaga (IT), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), University of Turin (IT), Università della Svizzera italiana (CH), University of Genoa (IT)
Openalex Percentile: Top 48%
Multiple Sclerosis Research Studies
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