Identification of a conserved sequence of disease progression in Idiopathic Pulmonary Fibrosis

We identified a conserved sequential decline in lung function in IPF, which has important implications for the design of clinical trials. The DPM provides a powerful framework to investigate the clinical and/or biological processes that initiate and propagate IPF.

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Publication Details

Journal
American Journal of Respiratory and Critical Care Medicine
Published
2026-02-13
DOI
https://doi.org/10.1093/ajrccm/aamag075
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of a conserved sequence of disease progression in Idiopathic Pulmonary Fibrosis

Jonathan A. Kropski, Peng Wu, Margaret L. Salisbury, Timothy S. Blackwell et al.
American Journal of Respiratory and Critical Care Medicine
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Identification of a conserved sequence of disease progression in Idiopathic Pulmonary Fibrosis

Jonathan A. Kropski, Peng Wu, Margaret L. Salisbury, Timothy S. Blackwell, Adam Guttentag, Melanie Quintana, Xiang Huang
article en

Abstract

We identified a conserved sequential decline in lung function in IPF, which has important implications for the design of clinical trials. The DPM provides a powerful framework to investigate the clinical and/or biological processes that initiate and propagate IPF.

American Journal of Respiratory and Critical Care Medicine
Vanderbilt University (US), University of Michigan (US), Berry & Associates (United States) (US), Nashville VA Medical Center (US), Michigan Medicine (US), Department of Veterans Affairs (AU), Vanderbilt University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 46%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Identification of a conserved sequence of disease progression in Idiopathic Pulmonary Fibrosis — Jonathan A. Kropski, Peng Wu, et al. · American Journal of Respiratory and Critical Care Medicine (2026) | TGRS Research Map | TGRS