Kynurenine pathway activation in ectopic pregnancy: diagnostic value of 3-hydroxykynurenine and 3-hydroxyanthranilic acid; a prospective study

These findings suggest that elevated 3-HK and 3-HAA levels are associated with EP and may reflect immunometabolic dysregulation underlying abnormal implantation, rather than implying a causal relationship. Therefore, these metabolites may offer complementary biomarker potential in selected research settings.

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Publication Details

Journal
Scandinavian Journal of Clinical and Laboratory Investigation
Published
2026-02-17
DOI
https://doi.org/10.1080/00365513.2026.2633556
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Kynurenine pathway activation in ectopic pregnancy: diagnostic value of 3-hydroxykynurenine and 3-hydroxyanthranilic acid; a prospective study

Oğuzhan Günenç, F. Sak, Fatma Sengul-Bag, Fadime Ovali et al.
Scandinavian Journal of Clinical and Laboratory Investigation
Tryptophan and brain disorders
article

Kynurenine pathway activation in ectopic pregnancy: diagnostic value of 3-hydroxykynurenine and 3-hydroxyanthranilic acid; a prospective study

Oğuzhan Günenç, F. Sak, Fatma Sengul-Bag, Fadime Ovali, Pinar Aytan-Tomas, Husamettin Vatansev, Sevcan Sarikaya
article en

Abstract

These findings suggest that elevated 3-HK and 3-HAA levels are associated with EP and may reflect immunometabolic dysregulation underlying abnormal implantation, rather than implying a causal relationship. Therefore, these metabolites may offer complementary biomarker potential in selected research settings.

Scandinavian Journal of Clinical and Laboratory InvestigationVol. 86(2)
Selçuk University (TR), Hai phong University Of Medicine and Pharmacy (VN), Konya Eğitim ve Araştırma Hastanesi (TR)
Good health and well-being
Openalex Percentile: Top 52%
Tryptophan and brain disorders
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