Impact of itopride on functional dyspepsia symptom progression: a multicenter noninterventional postregistration study

Itopride appears to be a safe and effective treatment for reducing symptom severity in patients with FD. The findings support the use of itopride in clinical settings, providing evidence of its benefit in managing this challenging condition. This study brings additional clinical knowledge from the eastern European population (Czechs) to data published by the ROME IV foundation with various cohorts of patients with FD and its results further demonstrate the long-term benefits and safety profile of itopride with minimal non-AEs.

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Publication Details

Journal
Therapeutic Advances in Gastroenterology
Published
2026-02-21
DOI
https://doi.org/10.1177/17562848261417732
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
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article

Impact of itopride on functional dyspepsia symptom progression: a multicenter noninterventional postregistration study

Radek Kroupa, Serhiy Forostyak, Michal Novotný, Tomas Pavlik et al.
Therapeutic Advances in Gastroenterology
Gastrointestinal motility and disorders
article

Impact of itopride on functional dyspepsia symptom progression: a multicenter noninterventional postregistration study

Radek Kroupa, Serhiy Forostyak, Michal Novotný, Tomas Pavlik, Jolien Schol, Jan Tack, Jiri Dolina, Ilja Tachecí, Martin Bortlík
article en

Abstract

Itopride appears to be a safe and effective treatment for reducing symptom severity in patients with FD. The findings support the use of itopride in clinical settings, providing evidence of its benefit in managing this challenging condition. This study brings additional clinical knowledge from the eastern European population (Czechs) to data published by the ROME IV foundation with various cohorts of patients with FD and its results further demonstrate the long-term benefits and safety profile of itopride with minimal non-AEs.

Therapeutic Advances in GastroenterologyVol. 19
Charles University (CZ), Masaryk University (CZ), University Hospital Brno (CZ), Nemocnice České Budějovice (CZ), University Hospital Hradec Králové (CZ)
Openalex Percentile: Top 45%
Gastrointestinal motility and disorders
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