Combined application of double plasma molecular adsorption system treatment, plasma exchange, and continuous veno-venous hemofiltration to rescue an adult patient with acute liver failure induced by accidental acute severe thinner intoxication: a cas

Thinner intoxication is a rare but non-negligible etiology of acute liver failure. To the best of our knowledge, our case is the first attempt to combine double plasma molecular adsorption system treatment, plasma exchange, and continuous veno-venous hemofiltration for acute liver failure as a clinical manifestation of thinner intoxication. The combination of different therapeutic modalities of an artificial liver support system can compensate for the individual shortcomings and maximize their respective advantages, which requires a multidisciplinary team to determine their clinical application in suitable patients.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-02-21
DOI
https://doi.org/10.1186/s13256-026-05871-w
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
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article

Combined application of double plasma molecular adsorption system treatment, plasma exchange, and continuous veno-venous hemofiltration to rescue an adult patient with acute liver failure induced by accidental acute severe thinner intoxication: a cas

Kai Kang, Huan Xin Meng, Jiang Xc, Yu-Jia Tang et al.
Journal of Medical Case Reports
Drug-Induced Hepatotoxicity and Protection
article

Combined application of double plasma molecular adsorption system treatment, plasma exchange, and continuous veno-venous hemofiltration to rescue an adult patient with acute liver failure induced by accidental acute severe thinner intoxication: a cas

Kai Kang, Huan Xin Meng, Jiang Xc, Yu-Jia Tang, J. Zhang, Dong-sheng Fei, Huiying Liu, Xiao-Fei Bi, J Y Xu, Kuo Wang, Ying-Fei Zhi, Di Wu, Yang Gao
article en

Abstract

Thinner intoxication is a rare but non-negligible etiology of acute liver failure. To the best of our knowledge, our case is the first attempt to combine double plasma molecular adsorption system treatment, plasma exchange, and continuous veno-venous hemofiltration for acute liver failure as a clinical manifestation of thinner intoxication. The combination of different therapeutic modalities of an artificial liver support system can compensate for the individual shortcomings and maximize their respective advantages, which requires a multidisciplinary team to determine their clinical application in suitable patients.

Journal of Medical Case ReportsVol. 20(1)
Harbin Medical University (CN), Second Affiliated Hospital of Harbin Medical University (CN), First Affiliated Hospital of Harbin Medical University (CN)
Openalex Percentile: Top 46%
Drug-Induced Hepatotoxicity and Protection
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