The pharmacokinetics and safety of vonoprazan in adolescents and children with gastroesophageal reflux disease

Exposures of vonoprazan in adolescents and children were nearly identical to exposures observed in adults, confirming the appropriateness of vonoprazan 10 and 20 mg doses in a pediatric population.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-02-21
DOI
https://doi.org/10.1002/jpn3.70368
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The pharmacokinetics and safety of vonoprazan in adolescents and children with gastroesophageal reflux disease

David A. Gremse, Axel Facius, Galen Witt, Eckhard Leifke et al.
Journal of Pediatric Gastroenterology and Nutrition
Gastroesophageal reflux and treatments
article

The pharmacokinetics and safety of vonoprazan in adolescents and children with gastroesophageal reflux disease

David A. Gremse, Axel Facius, Galen Witt, Eckhard Leifke, Darcy J. Mulford, Yu‐Ming Chang, Thomas Wagner
article en

Abstract

Exposures of vonoprazan in adolescents and children were nearly identical to exposures observed in adults, confirming the appropriateness of vonoprazan 10 and 20 mg doses in a pediatric population.

Journal of Pediatric Gastroenterology and Nutrition
Li Creative Technologies (United States) (US), University of South Alabama (US)
Good health and well-being
Openalex Percentile: Top 45%
Gastroesophageal reflux and treatments
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