β-casomorphin-7: a review of occurrence, identification, techno-functionality, and effects on human health
β-casomorphin-7 (βCM-7) is a bioactive peptide released after the digestion of β-casein A1 variant, mostly found in European cow breeds' milk. This review explores the occurrence, characteristics, identification, techno-functionality, and the potential health effects of βCM-7. It displays opioid-like properties because of its affinity for μ-opioid receptors, affecting both food texture and biological functions. βCM-7 has potential advantages on immune and gastrointestinal health; however, concerns persist regarding its adverse effects.
Authors
- Shao‐Quan Liu (ORCID: https://orcid.org/0000-0003-0868-2731)
- Gafar Babatunde Bamigbade (ORCID: https://orcid.org/0000-0003-2455-8183)
- Mayssa Hachem (ORCID: https://orcid.org/0000-0003-1986-8304)
- Zain Najjar
- Abdelmoneim H. Ali
- Mutamed Ayyash
Institutions
- National University of Singapore (SG)
- Khalifa University of Science and Technology (AE)
- United Arab Emirates University (AE)
Publication Details
- Journal
- npj Science of Food
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1038/s41538-026-00762-2
- Primary Topic
- Protein Hydrolysis and Bioactive Peptides
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- United Arab Emirates University