An international collaborative initiative to screen primary ciliary dyskinesia with high-speed video microscopy and nasal nitric oxide at a tertiary referral centre in South India
In resource-limited settings, diagnosis of PCD is often delayed. A combined screening strategy using HSVA and nasal NO testing can help identify likely PCD cases and facilitate early intervention. HSVA and nNO testing were found to be complementary in the screening of PCD. Genetic testing was used in a subset of patients to confirm diagnosis and was conclusive in 54% of tested.
Authors
- Kalyanasundaram Muthuswamy
- Jane Lucas
- Jacinta S. D’Souza (ORCID: https://orcid.org/0000-0003-2271-3653)
- Ram Ganesh
- Antony Terance Benjamin (ORCID: https://orcid.org/0000-0002-9657-1267)
- Claire Jackson
- Vijayakumar Raju
- Janice Coles
- Madhumitha Subramanium
- K. Madhumitha
- Sharada Iyer
Institutions
- University Hospital Southampton NHS Foundation Trust (GB)
- G. Kuppuswamy Naidu Memorial Hospital (IN)
- Center for Excellence in Basic Sciences (IN)
- University of Southampton (GB)
Publication Details
- Journal
- Lung India
- Published
- 2026-02-21
- DOI
- https://doi.org/10.4103/lungindia.lungindia_417_25
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00