The effect of neoadjuvant radiotherapy on immune cell infiltrates in myxofibrosarcoma

Conventional nRT is associated with reduced cytotoxic and helper T cell infiltration and increased presence of NK cells in MFS. These results suggest that conventional nRT reduces inflammatory aspects of MFS tumors.

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Publication Details

Journal
Immuno-Oncology Technology
Published
2026-02-21
DOI
https://doi.org/10.1016/j.iotech.2026.101586
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

The effect of neoadjuvant radiotherapy on immune cell infiltrates in myxofibrosarcoma

P.M. Braam, J. De Wilt, Emiel Ruijter, H.V.N. Küsters-Vandevelde et al.
Immuno-Oncology Technology
Sarcoma Diagnosis and Treatment
article

The effect of neoadjuvant radiotherapy on immune cell infiltrates in myxofibrosarcoma

P.M. Braam, J. De Wilt, Emiel Ruijter, H.V.N. Küsters-Vandevelde, Kiek Verrijp
article en

Abstract

Conventional nRT is associated with reduced cytotoxic and helper T cell infiltration and increased presence of NK cells in MFS. These results suggest that conventional nRT reduces inflammatory aspects of MFS tumors.

Immuno-Oncology TechnologyVol. 30
Radboud University Nijmegen (NL), Gelre Hospitals (NL), Catharina Ziekenhuis (NL), Radboud University Medical Center (NL), Canisius-Wilhelmina Ziekenhuis (NL), Rijnstate Hospital (NL), Jeroen Bosch Ziekenhuis (NL)
Zero hunger
Openalex Percentile: Top 47%
Sarcoma Diagnosis and Treatment
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