Aspirin use, lipoprotein(a), and calcific aortic valve disease: the Multi-ethnic Study of Atherosclerosis
In this exploratory analysis of prospective observational cohort data, regular aspirin use was associated with a lower risk of AVC and severe AS in persons with high Lp(a), but not high LDL-C. Confirmatory studies are required to determine the role of aspirin in the prevention of AVC and AS for persons with high Lp(a).
Authors
- M. Blaha
- M. Budoff
- George Thanassoulis (ORCID: https://orcid.org/0000-0002-9930-7189)
- Natalie Marrero (ORCID: https://orcid.org/0009-0006-1938-9679)
- L. Sperling
- Harpreet Singh Bhatia (ORCID: https://orcid.org/0000-0002-3964-2989)
- Seamus P. Whelton (ORCID: https://orcid.org/0000-0001-5914-0735)
- Michael Tsai
- K N Khurram Nasir
- Viola Vaccarino
- Sotirios Tsimikas
- Ramachandran S Vasan
- Omar Dzaye
- Roger S Blumenthal
- Alexander C Razavi
- Wendy S Post
Institutions
- Houston Methodist (US)
- University of Minnesota (US)
- Johns Hopkins University (US)
- Emory University (US)
- The University of Texas at San Antonio Health Science Center (US)
- Johns Hopkins Medicine (US)
- UCLA Medical Center (US)
- McGill University Health Centre (CA)
- Jackson Memorial Hospital (US)
- University of California San Diego (US)
- Emory Clinic (US)
- McGill Genome Centre (CA)
- The University of Texas at San Antonio (US)
Publication Details
- Journal
- European Heart Journal
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1093/eurheartj/ehag018
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00