Therapeutic Potential of Quercetin on A Rat Model of Radiation-Induced Brain Neurotoxicities: Insights from Behavioural and Biochemical Analyses.
The Quercetin exhibited a protective effect against radiation-induced neurotoxicity in the adult male Wistar rats by improving behavioural, biochemical, and histological outcomes. The 5 mg/kg dose provided the most consistent benefit. These findings suggest that quercetin, particularly at 5 mg/kg, could serve as a potential adjunctive therapy to mitigate neurotoxic side effects associated with RT.
Authors
- Mohammad Baqerzadeh Hosseini (ORCID: https://orcid.org/0000-0001-9747-607X)
- D. Moslemi
- Sohrab Kazemi
- Fereshteh Pourabdolhossein (ORCID: https://orcid.org/0000-0001-9285-1571)
- Manouchehr Ashrafpour (ORCID: https://orcid.org/0009-0005-2426-8284)
- Danial Sarrut
- Fatemeh Khani
- Ali-Akbar Moghadamnia
Institutions
- Islamic Azad University, Babol
- Babol University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-17
- DOI
- https://doi.org/10.22074/cellj.2025.2046460.1730
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00