Therapeutic Potential of Quercetin on A Rat Model of Radiation-Induced Brain Neurotoxicities: Insights from Behavioural and Biochemical Analyses.

The Quercetin exhibited a protective effect against radiation-induced neurotoxicity in the adult male Wistar rats by improving behavioural, biochemical, and histological outcomes. The 5 mg/kg dose provided the most consistent benefit. These findings suggest that quercetin, particularly at 5 mg/kg, could serve as a potential adjunctive therapy to mitigate neurotoxic side effects associated with RT.

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Publication Details

Journal
PubMed
Published
2026-02-17
DOI
https://doi.org/10.22074/cellj.2025.2046460.1730
Primary Topic
Effects of Radiation Exposure
Type
article
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article

Therapeutic Potential of Quercetin on A Rat Model of Radiation-Induced Brain Neurotoxicities: Insights from Behavioural and Biochemical Analyses.

Mohammad Baqerzadeh Hosseini, D. Moslemi, Sohrab Kazemi, Fereshteh Pourabdolhossein et al.
PubMed
Effects of Radiation Exposure
article

Therapeutic Potential of Quercetin on A Rat Model of Radiation-Induced Brain Neurotoxicities: Insights from Behavioural and Biochemical Analyses.

Mohammad Baqerzadeh Hosseini, D. Moslemi, Sohrab Kazemi, Fereshteh Pourabdolhossein, Manouchehr Ashrafpour, Danial Sarrut, Fatemeh Khani, Ali-Akbar Moghadamnia
article en

Abstract

The Quercetin exhibited a protective effect against radiation-induced neurotoxicity in the adult male Wistar rats by improving behavioural, biochemical, and histological outcomes. The 5 mg/kg dose provided the most consistent benefit. These findings suggest that quercetin, particularly at 5 mg/kg, could serve as a potential adjunctive therapy to mitigate neurotoxic side effects associated with RT.

PubMedVol. 27(1)
Islamic Azad University, Babol, Babol University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 48%
Effects of Radiation Exposure
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