Radiation-induced interferon-I response impairs thyroid organoid function
These results highlight the dual role of interferon-β signaling in modulating thyroid cell fate after irradiation, potentially promoting survival upon injury at the expense of regenerative potential.
Authors
- Abel Soto-Gamez (ORCID: https://orcid.org/0000-0001-8975-1377)
- Anne L. Jellema-de Bruin (ORCID: https://orcid.org/0000-0002-3586-738X)
- Rufina Maturi (ORCID: https://orcid.org/0009-0006-0493-3651)
- Davide Cinat (ORCID: https://orcid.org/0000-0001-8005-767X)
- Gabriella Esposito De Vita
- Rob P. Coppes
- Schelto Kruijff
Institutions
- University Medical Center Groningen (NL)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1016/j.radonc.2026.111453
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00