Review of research advances in the cerebral lymphatic system and neurological disorders

Evidence suggests that the targeted modulation of the cerebral lymphatic system has the potential to treat various neurological diseases. Nevertheless, our understanding of the molecular mechanisms remains in its early stages, with significant research gaps. Consequently, future investigations should focus on molecular characterization to identify specific therapeutic targets, thereby facilitating the translation of preclinical insights into clinical practice.

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Publication Details

Journal
Journal of Advanced Research
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jare.2026.02.032
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
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article

Review of research advances in the cerebral lymphatic system and neurological disorders

Zhaoxia Xie, Jiayi Wei, Jue Wang
Journal of Advanced Research
Cerebrospinal fluid and hydrocephalus
article

Review of research advances in the cerebral lymphatic system and neurological disorders

Zhaoxia Xie, Jiayi Wei, Jue Wang
article en

Abstract

Evidence suggests that the targeted modulation of the cerebral lymphatic system has the potential to treat various neurological diseases. Nevertheless, our understanding of the molecular mechanisms remains in its early stages, with significant research gaps. Consequently, future investigations should focus on molecular characterization to identify specific therapeutic targets, thereby facilitating the translation of preclinical insights into clinical practice.

Journal of Advanced Research
Ministry of Education (KR), China Medical University (CN)
Openalex Percentile: Top 47%
Cerebrospinal fluid and hydrocephalus
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