Long-Term Survival with Daratumumab, Lenalidomide and Dexamethasone in Transplant-Ineligible Newly Diagnosed Multiple Myeloma Patients—A Survey from Two Italian Centers
This study confirms the efficacy of the D-Rd combination as first-line therapy for TIE-NDMM patients, suggesting that achieving at least a PR-and particularly a VGPR-may represent a strong predictor of long-term remission and survival, even in the era of new combinations based on the use of quadruplets.
Authors
- Giuseppina Uccello
- Veronica Vecchio
- Manlio Fazio (ORCID: https://orcid.org/0000-0001-8804-2640)
- Vittorio Del Fabro (ORCID: https://orcid.org/0009-0000-4405-2716)
- Federica Elia (ORCID: https://orcid.org/0000-0002-2449-5808)
- Fabio Stagno (ORCID: https://orcid.org/0000-0002-7947-158X)
- Claudia Bellofiore (ORCID: https://orcid.org/0000-0002-4388-1835)
- Cristina Lo Faro
- Ugo Consoli (ORCID: https://orcid.org/0009-0002-0249-3411)
- Chiara Maria Catena Sorbello
- Concetta Conticello
- Alessandra Romano
- Francesco Di Raimondo
- Giuliana Giunta
- Dario Leotta
- Lara Gullo
Institutions
- University of Messina (IT)
- Università degli Studi di Enna Kore (IT)
- University of Catania (IT)
- Ospedale Garibaldi (IT)
- Policlinico Universitario di Catania (IT)
- Azienda Ospedaliera Universitaria Policlinico "G. Martino" (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
Publication Details
- Journal
- Diseases
- Published
- 2026-02-21
- DOI
- https://doi.org/10.3390/diseases14020081
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00