Foramen Magnum Stenosis in Achondroplasia: Imaging-Based Surgical Indications, Synchondrosis Fusion, and the Role of Ventriculomegaly

FMS in achondroplasia poses major risks, yet its natural history and management remain unclear. Our findings support early imaging-based screening and timely intervention in cases with cord compression. While FMD effectively relieves compression, it does not address underlying ossification abnormalities, requiring continued surveillance. Premature synchondrosis fusion may play a key role, and future studies should consider combined surgical and medical approaches to improve outcomes.

Authors

Publication Details

Journal
Pediatric Neurosurgery
Published
2026-02-21
DOI
https://doi.org/10.1159/000551092
Primary Topic
Connective tissue disorders research
Type
article
Field-Weighted Citation Impact
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article

Foramen Magnum Stenosis in Achondroplasia: Imaging-Based Surgical Indications, Synchondrosis Fusion, and the Role of Ventriculomegaly

Osamu Numata, Ryo Ando
Pediatric Neurosurgery
Connective tissue disorders research
article

Foramen Magnum Stenosis in Achondroplasia: Imaging-Based Surgical Indications, Synchondrosis Fusion, and the Role of Ventriculomegaly

Osamu Numata, Ryo Ando
article en

Abstract

FMS in achondroplasia poses major risks, yet its natural history and management remain unclear. Our findings support early imaging-based screening and timely intervention in cases with cord compression. While FMD effectively relieves compression, it does not address underlying ossification abnormalities, requiring continued surveillance. Premature synchondrosis fusion may play a key role, and future studies should consider combined surgical and medical approaches to improve outcomes.

Pediatric Neurosurgery
Good health and well-being
Openalex Percentile: Top 45%
Connective tissue disorders research
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Foramen Magnum Stenosis in Achondroplasia: Imaging-Based Surgical Indications, Synchondrosis Fusion, and the Role of Ventriculomegaly — Osamu Numata, Ryo Ando · Pediatric Neurosurgery (2026) | TGRS Research Map | TGRS