New-onset urinary symptoms following marriage leading to discovery of inverted urothelial papilloma in a young female: A case report

Persistent urinary symptoms, such as dysuria and urgency in young women, despite treatment for postcoital urinary tract infections commonly termed "honeymoon cystitis," warrant evaluation for rare entities such as inverted urothelial papilloma (IUP), a benign neoplasm uncommonly seen in young females, with diagnosis confirmed histopathologically, given its potential to mimic recurrent UTI. A 25-year-old newly married female developed recurrent urinary tract infection symptoms shortly after marriage, with only partial improvement with antibiotics. Persistent symptoms prompted imaging and cystoscopy, revealing lesions on the right lateral bladder wall. Transurethral resection and histopathological examination confirmed an inverted urothelial papilloma. This case emphasizes the necessity of broad differential diagnosis in persistent urinary symptoms and highlights the importance of early imaging and cystoscopy. Long-term surveillance is warranted due to potential recurrence of IUP, even in young patients.

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Publication Details

Journal
Radiology Case Reports
Published
2026-02-22
DOI
https://doi.org/10.1016/j.radcr.2026.01.049
Primary Topic
Urological Disorders and Treatments
Type
article
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article

New-onset urinary symptoms following marriage leading to discovery of inverted urothelial papilloma in a young female: A case report

Hanood Abu-Rass, Hatim Hijaz, Ibraheem Alami, Razi Sulaiman et al.
Radiology Case Reports
Urological Disorders and Treatments
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New-onset urinary symptoms following marriage leading to discovery of inverted urothelial papilloma in a young female: A case report

Hanood Abu-Rass, Hatim Hijaz, Ibraheem Alami, Razi Sulaiman, Momen Sawafta, Razan kalboneh, Mazen Badaha, Manar Badaha, Malak Badaha
article en

Abstract

Persistent urinary symptoms, such as dysuria and urgency in young women, despite treatment for postcoital urinary tract infections commonly termed "honeymoon cystitis," warrant evaluation for rare entities such as inverted urothelial papilloma (IUP), a benign neoplasm uncommonly seen in young females, with diagnosis confirmed histopathologically, given its potential to mimic recurrent UTI. A 25-year-old newly married female developed recurrent urinary tract infection symptoms shortly after marriage, with only partial improvement with antibiotics. Persistent symptoms prompted imaging and cystoscopy, revealing lesions on the right lateral bladder wall. Transurethral resection and histopathological examination confirmed an inverted urothelial papilloma. This case emphasizes the necessity of broad differential diagnosis in persistent urinary symptoms and highlights the importance of early imaging and cystoscopy. Long-term surveillance is warranted due to potential recurrence of IUP, even in young patients.

Radiology Case ReportsVol. 21(5)
An-Najah National University (PS)
Gender equality
Openalex Percentile: Top 46%
Urological Disorders and Treatments
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