Imaging-derived neuromuscular ultrasound phenotypes are associated with functional status in amyotrophic lateral sclerosis
Integrating NMUS with clinical data enables objective, imaging-derived stratification of ALS patients into biologically and functionally distinct subgroups. This approach offers a pragmatic framework for phenotypic characterization and may inform personalized monitoring and trial design in ALS.
Authors
- Junlin Ding
- Tianhua Yang
- Ting Lin
- Hao Zhang
- Min Zhao
- Yuxuan Qiu
- Xinyi Yan
- Ying Wang
- Jialei Luo
- Gaoyi Yang
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Normal University (CN)
- Westlake University (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1007/s00415-026-13705-4
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00