The Complementary Roles of EBUS-Guided Needle Aspiration, Mini-Forceps, and Cryobiopsy in the Investigation of Mediastinal Lesions
For the sampling of mediastinal and hilar lesions, supplementation of EBUS-TBNA by TBFB or TBCB should be primarily considered when suspecting a lymphoproliferative or an inflammatory etiology or when high-quality tissue is required for predictive immunohistochemistry, and molecular assays. For accurate diagnosis and classification of lymphomas, the combination of TBNA for flow cytometry with TBCB for histopathologic interpretation appears to be optimal.
Authors
- Alexander D. Drilon
- Van K. Holden (ORCID: https://orcid.org/0000-0002-5430-3344)
- Rastko Rakočević
- Paul J. Christos (ORCID: https://orcid.org/0000-0002-3211-9503)
- A. Sachdeva
- Teklu Legesse
- L. Falchi
- Xiaoyue Ma (ORCID: https://orcid.org/0000-0002-1560-4443)
- Romany Auclair (ORCID: https://orcid.org/0000-0003-1308-7363)
- Edward M. Pickering (ORCID: https://orcid.org/0000-0001-9873-4974)
- Bryan C. Husta
- Brie E. Kezlarian-Sachs
- Oscar Lin
- Catherine L Oberg
- Robert P Lee
- Jason C Chang
Institutions
- University of Maryland, Baltimore (US)
- Memorial Sloan Kettering Cancer Center (US)
- Cornell University (US)
- Pulmonary and Critical Care Associates (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Annals of the American Thoracic Society
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1093/annalsats/aaoag040
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00