Natural bioactive molecules and chemotherapeutics synergism for enhanced cancer therapy
Integrating natural bioactives with conventional chemotherapy represents a promising strategy to enhance therapeutic index by concurrently amplifying antitumor mechanisms and mitigating dose‑limiting toxicities, though broader clinical validation and standardized quality controls are needed for routine adoption.
Authors
- Mina Alimohammadi (ORCID: https://orcid.org/0000-0002-5953-3894)
- Afshin Taheriazam (ORCID: https://orcid.org/0000-0002-3907-925X)
- Neda Zali
- Sevda Nasirzade
- Mehrdad HSAhemi
- W. V. Cho
- Vahid Tavakolpour (ORCID: https://orcid.org/0000-0002-8785-6084)
- Maliheh Entezari (ORCID: https://orcid.org/0000-0003-4191-3351)
- Payman Rahimzadeh
- Ali Vasheghani Farahani (ORCID: https://orcid.org/0009-0007-0783-6475)
- Katayoun Heshmatzad
- Saba Mashhadikhan
- Kiavash Hushmandi
- Sara Komeilie Esfahani
- Ghazaleh Shahsavan
- Pardis Karimi
- Naghmeh Beikzadeh
- Ehsan Maghrebi-Ghojogh
Institutions
- Islamic Azad University, Tehran (IR)
- University of Calgary (CA)
- University of Tehran (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- National Institute of Genetic Engineering and Biotechnology (IR)
- Queen Elizabeth Hospital (CN)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
- Mazandaran University of Medical Sciences (IR)
Publication Details
- Journal
- Nutrition & Metabolism
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1186/s12986-026-01094-4
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00