Unresectable Alveolar Rhabdomyosarcoma: An Unusual Presentation

REPORTbony metastasis in bilateral iliac bones.However, bone marrow biopsy done on November 19, 2024 and technetium (Tc-99) bone scan done on September 3, 2024 showed no evidence of bony metastasis.Biopsy from the lesion was suggestive of a malignant round cell tumor.Immunohistochemistry (IHC) showed the tumor to be desmin-, myogenin-, and myoD1-positive, which suggested a diagnosis of alveolar RMS (Figs 3 to 6).The tumor was deemed unresectable by the Uro-oncology Department and was started on chemotherapy with the VAC IRS-IV protocol which consisted of weekly vincristine 2 mg, actinomycin-D 1 mg, and cyclophosphamide 3400 mg.

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Publication Details

Journal
Gujarat Cancer Society Research Journal
Published
2026-02-12
DOI
https://doi.org/10.5005/gcsrj-11042-0012
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Unresectable Alveolar Rhabdomyosarcoma: An Unusual Presentation

Shubham Koirala, Kevin S. Mistry, Ankita Parikh, Umang Kardani et al.
Gujarat Cancer Society Research Journal
Sarcoma Diagnosis and Treatment
article

Unresectable Alveolar Rhabdomyosarcoma: An Unusual Presentation

Shubham Koirala, Kevin S. Mistry, Ankita Parikh, Umang Kardani, Akash Pandya
article en

Abstract

REPORTbony metastasis in bilateral iliac bones.However, bone marrow biopsy done on November 19, 2024 and technetium (Tc-99) bone scan done on September 3, 2024 showed no evidence of bony metastasis.Biopsy from the lesion was suggestive of a malignant round cell tumor.Immunohistochemistry (IHC) showed the tumor to be desmin-, myogenin-, and myoD1-positive, which suggested a diagnosis of alveolar RMS (Figs 3 to 6).The tumor was deemed unresectable by the Uro-oncology Department and was started on chemotherapy with the VAC IRS-IV protocol which consisted of weekly vincristine 2 mg, actinomycin-D 1 mg, and cyclophosphamide 3400 mg.

Gujarat Cancer Society Research JournalVol. 27(2)
Openalex Percentile: Top 47%
Sarcoma Diagnosis and Treatment
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