A comparison of customized GPTs and GPT-4o for self-medication knowledge: A feasibility study using the Japanese registered salesperson examination

This feasibility study demonstrates that minimal customization through reference materials upload can achieve performance improvements on knowledge-based assessments. However, examination performance represents only an indirect indicator of knowledge for self-medication support. Future research should evaluate LLMs performance in real-world case scenarios and assess practical utility and safety before implementation in consumer self-medication settings.

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Publication Details

Journal
Digital Health
Published
2026-02-01
DOI
https://doi.org/10.1177/20552076261427504
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

A comparison of customized GPTs and GPT-4o for self-medication knowledge: A feasibility study using the Japanese registered salesperson examination

Shota Okazaki, Yuichi Mine, Takeshi MURAYAMA, Saori Takeda
Digital Health
Artificial Intelligence in Healthcare and Education
article

A comparison of customized GPTs and GPT-4o for self-medication knowledge: A feasibility study using the Japanese registered salesperson examination

Shota Okazaki, Yuichi Mine, Takeshi MURAYAMA, Saori Takeda
article en

Abstract

This feasibility study demonstrates that minimal customization through reference materials upload can achieve performance improvements on knowledge-based assessments. However, examination performance represents only an indirect indicator of knowledge for self-medication support. Future research should evaluate LLMs performance in real-world case scenarios and assess practical utility and safety before implementation in consumer self-medication settings.

Digital HealthVol. 12
Hiroshima University (JP), Sapporo City University (JP)
Quality Education
Openalex Percentile: Top 50%
Artificial Intelligence in Healthcare and Education
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