Abstract PS5-10-14: How Reliable is YouTube Content Targeting Arabic-Speaking Breast Cancer Patients Regarding Post-Mastectomy Reconstruction?

Abstract Background: The dynamic, easily accessible nature of social media platforms, particularly YouTube (YT), has revolutionized the way breast cancer patients seek and process information. This study evaluates the quality of YT videos addressing post-mastectomy reconstruction (PMR) that target Arabic-speaking women (ASW), a heavily digitally connected segment of society that may experience challenges in accessing mainstream medical information in Arabic Language (AL). Methods: YT was searched incognito, using the terms: "post mastectomy reconstruction" in (AL) in July 2023. Data collected included upload date, video length, source, sponsorship, and viewer engagement. Thematic content analysis was performed by physician reviewers. Understandability and actionability were assessed using the Patient Education Materials Assessment Tool (PEMAT A/V), and video quality was evaluated using the DISCERN tool. Cluster analysis used to categorize the videos based on quality. Results: A total of 109 videos were included. The average video length was 7 minutes (SD 10.2). Most originated from North Africa (55%), followed by the Persian Gulf (33%) and the Mediterranean region (11%). Videos were predominantly created by individuals (57.8%) and were natively in Arabic (93.6%). Mean views per video were 8,052. Most videos were information-based (92.6%), aimed at the public (82%), and commercially sponsored (62%). PMBR visuals appeared in 31.1% of videos. Common themes included awareness (82.6%), appearance (68.8%), gender identity (57.8%), and treatment (45.0%); sexuality and fertility were least discussed (4.6%). While 99% encouraged PMR, only 34% offered actionable guidance. Mean PEMAT scores were 61.3% for understandability and 20.2% for actionability. The mean DISCERN score was 2.6/5, with only 43.1% of videos rated as recommendable by Arabic-speaking healthcare professionals. Cluster analysis showed only 19.3% of videos were high quality. High-quality videos were significantly longer (p=0.002), less commercially sponsored (p=0.001), more likely to be information- and advice-based, and more likely to include sensitive themes such as sexuality and fertility. Viewer engagement was not correlated with video quality. Conclusion: Arabic-language PMR content on YT has moderate quality, easily understandable but lacks actionability and patient-centered depth. Videos are highly sponsored and questionably representative of patients’ and women’s perspective. Improving content quality is essential to support informed decision-making among ASW exploring PMR. Citation Format: H. Alotaibi, A. Alsulaimani, M. Alsuhaibani, E. Belzile, N. Morena, A. Meguerditchian. How Reliable is YouTube Content Targeting Arabic-Speaking Breast Cancer Patients Regarding Post-Mastectomy Reconstruction? [abstract]. In: Proceedings of the San Antonio Breast Cancer Symposium 2025; 2025 Dec 9-12; San Antonio, TX. Philadelphia (PA): AACR; Clin Cancer Res 2026;32(4 Suppl):Abstract nr PS5-10-14