Comparative Analysis of 18F-FAPI and 18F-FDG PET/CT in Evaluation of Intestinal Lesions and Disease Activity in Ulcerative Colitis

The efficacy of 18F-FAPI PET/CT in the evaluation of intestinal lesions and disease activity assessment of UC was superior to that of 18F-FDG PET/CT. 18F-FAPI PET/CT also correlated well with endoscopy, abdominal contrast-enhanced CT, clinical manifestations, and biomarkers. Therefore, 18F-FAPI PET/CT may be a promising method for noninvasive assessment of disease activity of UC.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-02-11
DOI
https://doi.org/10.1097/rlu.0000000000006371
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Analysis of 18F-FAPI and 18F-FDG PET/CT in Evaluation of Intestinal Lesions and Disease Activity in Ulcerative Colitis

Weicheng Zhou, Chaoqun Lv, Xinxin Liu, Xinyue Hu et al.
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
article

Comparative Analysis of 18F-FAPI and 18F-FDG PET/CT in Evaluation of Intestinal Lesions and Disease Activity in Ulcerative Colitis

Weicheng Zhou, Chaoqun Lv, Xinxin Liu, Xinyue Hu, Zhenfang Yan, Kaijun Liu, Jinju Sun, Yi Ru, Wenbo Li, Wen Shi, Zhixue Liu, Feng Liu, Yuanyuan Ai, Xiang Li, Zhipeng Wen, Xiao Chen, Min Yang
article en

Abstract

The efficacy of 18F-FAPI PET/CT in the evaluation of intestinal lesions and disease activity assessment of UC was superior to that of 18F-FDG PET/CT. 18F-FAPI PET/CT also correlated well with endoscopy, abdominal contrast-enhanced CT, clinical manifestations, and biomarkers. Therefore, 18F-FAPI PET/CT may be a promising method for noninvasive assessment of disease activity of UC.

Clinical Nuclear Medicine
Army Medical University (CN), Daping Hospital (CN), Essex Cardiothoracic Centre (GB), Urumqi General Hospital of PLA (CN)
Openalex Percentile: Top 46%
Peptidase Inhibition and Analysis
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Comparative Analysis of 18F-FAPI and 18F-FDG PET/CT in Evaluation of Intestinal Lesions and Disease Activity in Ulcerative Colitis — Weicheng Zhou, Chaoqun Lv, et al. · Clinical Nuclear Medicine (2026) | TGRS Research Map | TGRS