From controversy to opportunity: experts weigh in on myeloid states as determinants in cancer immunotherapy
Across solid tumors, cells of the myeloid lineage—monocytes, macrophages, dendritic cells, and granulocytes—play major roles in cancer biology by regulating immune responses, angiogenesis, tumor cell invasion and metastasis, and treatment outcomes.
Authors
- Dmitry I. Gabrilovich (ORCID: https://orcid.org/0000-0001-9913-6407)
- Jennifer L. Guerriero (ORCID: https://orcid.org/0000-0002-2104-5457)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- AstraZeneca (Netherlands) (NL)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1136/jitc-2026-015058
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Array BioPharma
- Incyte
- Genentech