A pharmacovigilance analysis of carbapenem-related utilizing the FDA adverse event reporting system (FAERS) database from 2013 to 2025
Significant differences exist in haematologic safety profiles among carbapenems. Meropenem shows the broadest spectrum of severe toxicity, while other carbapenems demonstrate fewer reports. demonstrates fewer reported haematologic safety signals and not a most favourable haematologic safety profile. These differential safety profiles should inform further studies on carbapenem selection, including patients with baseline haematologic disorders.
Authors
- Connor Frey
- Parham Elmi
Institutions
- University of British Columbia (CA)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1093/jac/dkag060
- Citations
- 1
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 33.63