The Effect of High-Intensity Interval Training on Neuroplasticity-Related Proteins in the Cerebrum of Postnatally Growth-Restricted Mice

Contrary to expectations, HIIT did not elevate neuroplasticity markers in PNGR mice, highlighting the lasting impact of early-life growth restriction on brain plasticity and suggesting the need for alternative interventions.

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Publication Details

Journal
Medicine & Science in Sports & Exercise
Published
2026-02-17
DOI
https://doi.org/10.1249/mss.0000000000003964
Primary Topic
Neurogenesis and neuroplasticity mechanisms
Type
article
Field-Weighted Citation Impact
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article

The Effect of High-Intensity Interval Training on Neuroplasticity-Related Proteins in the Cerebrum of Postnatally Growth-Restricted Mice

Eric C. Leszczynski, Ashley C. McPeek, Melissa A. Quinn, David Ferguson et al.
Medicine & Science in Sports & Exercise
Neurogenesis and neuroplasticity mechanisms
article

The Effect of High-Intensity Interval Training on Neuroplasticity-Related Proteins in the Cerebrum of Postnatally Growth-Restricted Mice

Eric C. Leszczynski, Ashley C. McPeek, Melissa A. Quinn, David Ferguson, Julian Ananyev, Seong-Hyun Kim
article en

Abstract

Contrary to expectations, HIIT did not elevate neuroplasticity markers in PNGR mice, highlighting the lasting impact of early-life growth restriction on brain plasticity and suggesting the need for alternative interventions.

Medicine & Science in Sports & Exercise
Washington State Department of Health (US), University of South Carolina (US), Michigan State University (US)
Openalex Percentile: Top 57%
Neurogenesis and neuroplasticity mechanisms
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The Effect of High-Intensity Interval Training on Neuroplasticity-Related Proteins in the Cerebrum of Postnatally Growth-Restricted Mice — Eric C. Leszczynski, Ashley C. McPeek, et al. · Medicine & Science in Sports & Exercise (2026) | TGRS Research Map | TGRS