Primary Treatment Refractory Adult Wilms’ Tumor: A Case Report

REPORTdefect in the renal vein and renal and suprarenal IVC, suggestive of tumor thrombus, second and third part of duodenum with loss of fat plane (LOFP), and uncinate process of pancreas with LOFP, along with a 2.2 2 cm mid para-aortic lymph node, and no distant metastases were seen (Fig. 1).A core needle biopsy was done from the right renal fossa mass, which was suggestive of leiomyoma.T he p atient was re ferre d to our ins titution, and histopathological review showed a collection of fusiform to elongated cells, vascular proliferation, loose stroma, necrosis, and minimal pleomorphism with a possibility of a benign lesion.Immunohistochemistry (IHC) showed focal positivity for HMB45, EMA, and PAX8, positivity for actin, desmin, vimentin, H-caldesman, and negative Melan-A and AE1.He underwent right radical nephrectomy with thrombectomy with lymph node dissection.Surgical pathology specimen showed classical triphasic

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Publication Details

Journal
Gujarat Cancer Society Research Journal
Published
2026-02-12
DOI
https://doi.org/10.5005/gcsrj-11042-0013
Primary Topic
Renal and related cancers
Type
article
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article

Primary Treatment Refractory Adult Wilms’ Tumor: A Case Report

Goutham Sunny, Harsha P. Panchal, Aastha Shah, Parikh Sonia K et al.
Gujarat Cancer Society Research Journal
Renal and related cancers
article

Primary Treatment Refractory Adult Wilms’ Tumor: A Case Report

Goutham Sunny, Harsha P. Panchal, Aastha Shah, Parikh Sonia K, Praloy Basu, Apurva Patel
article en

Abstract

REPORTdefect in the renal vein and renal and suprarenal IVC, suggestive of tumor thrombus, second and third part of duodenum with loss of fat plane (LOFP), and uncinate process of pancreas with LOFP, along with a 2.2 2 cm mid para-aortic lymph node, and no distant metastases were seen (Fig. 1).A core needle biopsy was done from the right renal fossa mass, which was suggestive of leiomyoma.T he p atient was re ferre d to our ins titution, and histopathological review showed a collection of fusiform to elongated cells, vascular proliferation, loose stroma, necrosis, and minimal pleomorphism with a possibility of a benign lesion.Immunohistochemistry (IHC) showed focal positivity for HMB45, EMA, and PAX8, positivity for actin, desmin, vimentin, H-caldesman, and negative Melan-A and AE1.He underwent right radical nephrectomy with thrombectomy with lymph node dissection.Surgical pathology specimen showed classical triphasic

Gujarat Cancer Society Research JournalVol. 27(2)
Openalex Percentile: Top 47%
Renal and related cancers
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