Clinical characteristics of isolated perianal Crohn’s disease and validation of the TOpClass criteria: a retrospective cohort pilot study
ipCD represents a distinct phenotype with advanced fistula complexity and limited response to biologics. Younger age, anal stenosis, and more advanced fistula characteristics favor ipCD over CGD. Applying TOpClass criteria showed high specificity but moderate sensitivity; incorporating additional fistula features may improve sensitivity.
Authors
- Julajak Limsrivilai (ORCID: https://orcid.org/0000-0001-5867-0312)
- Sitthipong Srisajjakul (ORCID: https://orcid.org/0000-0002-2598-3037)
- Phichayut Phinyo (ORCID: https://orcid.org/0000-0002-8543-6254)
- Wasuwit Wanchaitanawong (ORCID: https://orcid.org/0000-0001-7221-4196)
- Marianee Salaemae
- Varut Lohsiriwat
Institutions
- Siriraj Hospital (TH)
- Chiang Mai University (TH)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1093/ibd/izag028
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00