Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI - The ADQI 32 consensus meeting

Despite advancements in obstetric care, pregnancy-associated acute kidney injury (PrAKI) continues to be a significant public health concern, contributing to substantial maternal and fetal morbidity and mortality. The most common causes of PrAKI include preeclampsia/eclampsia, haemorrhage, and infection. Diagnosis is influenced by gestational age and individual risk factors. Alongside traditional investigations such as imaging and kidney biopsy, novel diagnostics and biomarkers may provide valuable insights for differential diagnosis. This review aims to offer an update on the diagnostic approaches and investigational tools for PrAKI, while also addressing current challenges in the diagnostic paradigm and presenting recommendations for clinical practice and future research.

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Publication Details

Journal
Universität Zürich, ZORA
Published
2025-10-27
DOI
https://doi.org/10.5167/uzh-292165
Primary Topic
Acute Kidney Injury Research
Type
article
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article

Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI - The ADQI 32 consensus meeting

Ghada Ankawi, Anjali Acharya, Rolando Claure-Del Granado, Valerie A Luyckx et al.
Universität Zürich, ZORA
Acute Kidney Injury Research
article

Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI - The ADQI 32 consensus meeting

Ghada Ankawi, Anjali Acharya, Rolando Claure-Del Granado, Valerie A Luyckx, Ravindra L Mehta, ADQI 32 panel members, Marlies Ostermann, Cathy Nelson-Piercy, Swarnalata Gowrishankar, Nuttha Lumlertgul, Claudio Ronco
article en

Abstract

Despite advancements in obstetric care, pregnancy-associated acute kidney injury (PrAKI) continues to be a significant public health concern, contributing to substantial maternal and fetal morbidity and mortality. The most common causes of PrAKI include preeclampsia/eclampsia, haemorrhage, and infection. Diagnosis is influenced by gestational age and individual risk factors. Alongside traditional investigations such as imaging and kidney biopsy, novel diagnostics and biomarkers may provide valuable insights for differential diagnosis. This review aims to offer an update on the diagnostic approaches and investigational tools for PrAKI, while also addressing current challenges in the diagnostic paradigm and presenting recommendations for clinical practice and future research.

Universität Zürich, ZORA
Good health and well-being
Openalex Percentile: Top 25%
Acute Kidney Injury Research
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