Osteoarthritis is not a peri-operative risk factor or indicator of poor clinical outcomes with surgical correction for thoracolumbar scoliosis

Background: Understanding peri-operative influences of patients’ past medical history during spinal surgery is essential for promoting good clinical outcomes. A paucity of literature exists regarding the effect of common degenerative disorders like arthritis on spinal fusion outcomes. Methods: A retrospective review of a prospectively maintained database was utilized to examine patients undergoing spine fusion surgery at any spinal segment. Patients with a past medical history of arthritis were identified and analyzed for the following peri-operative events. Results: 532 patients met inclusion criteria, of which 192 suffered from comorbid osteoarthritis. Patients with arthritis were significantly older ( P <00.1), had a higher BMI ( P =0.0193), and were more likely to be former smokers ( P <0.001). When examining intra-operative features, the arthritic cohort construct length was significantly longer (5.79 vs. 6.55, P =0.0112). There were no significant differences in rates of intra-operative complication. Post-operatively, there were no differences in complications, either in surgical site infection ( P =0.89) or in the rate of venous thrombotic events ( P =1). On follow-up, there were no significant differences in rate of instrumentation failure ( P =0.11) or need for revision surgery ( P =0.32). Multivariable analysis demonstrated the same trend for all intra-operative findings and all post-operative observations. Conclusion: Arthritis was not associated with increased incidence of intra-operative complications or increased need for fusion revision for our cohort. The presence of arthritis did yield an increased intra-operative blood loss without clear clinical significance. These results suggest that the presence of additional degenerative inflammatory disease does not intrinsically yield a greater incidence of peri-operative complications or failure rates.

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Publication Details

Journal
Current Orthopaedic Practice
Published
2025-12-11
DOI
https://doi.org/10.1097/bco.0000000000001347
Primary Topic
Scoliosis diagnosis and treatment
Type
article
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0.00
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article

Osteoarthritis is not a peri-operative risk factor or indicator of poor clinical outcomes with surgical correction for thoracolumbar scoliosis

John V. Dang, Luke Mugge, Noah Diekemper, Danielle Dang et al.
Current Orthopaedic Practice
Scoliosis diagnosis and treatment
article

Osteoarthritis is not a peri-operative risk factor or indicator of poor clinical outcomes with surgical correction for thoracolumbar scoliosis

John V. Dang, Luke Mugge, Noah Diekemper, Danielle Dang, Joseph P. Gjolaj, Andrew J. Caras, Andrew A. Fanous, Barth A. Green
article en

Abstract

Background: Understanding peri-operative influences of patients’ past medical history during spinal surgery is essential for promoting good clinical outcomes. A paucity of literature exists regarding the effect of common degenerative disorders like arthritis on spinal fusion outcomes. Methods: A retrospective review of a prospectively maintained database was utilized to examine patients undergoing spine fusion surgery at any spinal segment. Patients with a past medical history of arthritis were identified and analyzed for the following peri-operative events. Results: 532 patients met inclusion criteria, of which 192 suffered from comorbid osteoarthritis. Patients with arthritis were significantly older ( P <00.1), had a higher BMI ( P =0.0193), and were more likely to be former smokers ( P <0.001). When examining intra-operative features, the arthritic cohort construct length was significantly longer (5.79 vs. 6.55, P =0.0112). There were no significant differences in rates of intra-operative complication. Post-operatively, there were no differences in complications, either in surgical site infection ( P =0.89) or in the rate of venous thrombotic events ( P =1). On follow-up, there were no significant differences in rate of instrumentation failure ( P =0.11) or need for revision surgery ( P =0.32). Multivariable analysis demonstrated the same trend for all intra-operative findings and all post-operative observations. Conclusion: Arthritis was not associated with increased incidence of intra-operative complications or increased need for fusion revision for our cohort. The presence of arthritis did yield an increased intra-operative blood loss without clear clinical significance. These results suggest that the presence of additional degenerative inflammatory disease does not intrinsically yield a greater incidence of peri-operative complications or failure rates.

Current Orthopaedic PracticeVol. 37(2)
Inova Health System (US), University of Miami (US), Virginia Commonwealth University (US), Neurosciences Institute (US), Walter Reed National Military Medical Center (US), Neurological Surgery (US)
No poverty
Openalex Percentile: Top 22%
Scoliosis diagnosis and treatment
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