Abstract PS5-10-09: Prognostic factor pregnancy associated breast cancer by assisted technical reproduction

Abstract Aims Study and assess the differences in the prognostic factors in pregnancy associated breast cancer by assisted technical reproduction and without . Methods Study 164 pregnancy associated breast cancer, 124 without assisted technical reproduction and 40 with assisted technical reproduction, treated in the same hospital. Analyze prognostic factors: estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 , histological grade and ki67, of pregnancy associated breast cancer with and without assisted technical reproduction. Results Patients with pregnancy associated breast cancer without assisted technical reproductio: estrogen receptor is positive in 91 (73’38 %), negative in 33 (26’61 %) patients with assisted technical reproduction ,estrogen receptor is positive in 34 (94’44 %), negative in 2 (5’55%) patients. (p<0’05), ki67 <20 in 50 (46’72%) patients and > 20 in 57 (53’27%) patients without assisted technical reproduction, and ki67 < 20 in 19 (67’85 %) patients, and Ki 67 >20 in 9 (32’14%) patients with assisted technical reproduction (p<0’05). Progesterone receptor and HER2 receptor there was no difference between with and without assisted tecnical reproduction. (p=ns). Conclusion. Pregnancy associated breast cancer by assisted technical reproduction influence estrogen receptor and Ki67, and do not influence progesterone receptor and HER2 receptor Citation Format: M. Izquierdo, S. Baulies, M. Gallardo, C. Ara, F. Fargas, F. Tresserra, R. Fabregas, P. Barri S. Prognostic factor pregnancy associated breast cancer by assisted technical reproduction [abstract]. In: Proceedings of the San Antonio Breast Cancer Symposium 2025; 2025 Dec 9-12; San Antonio, TX. Philadelphia (PA): AACR; Clin Cancer Res 2026;32(4 Suppl):Abstract nr PS5-10-09