Endoplasmic Reticulum Stress‐Induced Membrane Exposure of Calreticulin Serves as a Guide for Phagocytic Removal of Stressed‐But‐Viable Cytotrophoblasts
Our results thus propose a pathway for removal of damaged CTBs and thus for maintaining pregnancy. Because ER stress is a risk factor for poor placentation, investigation of physiological and pathological roles of CRT exposure-mediated phagocytic removal deserves future study.
Authors
- Naoyuki Iwahashi (ORCID: https://orcid.org/0000-0002-6422-325X)
- Kazuchika Nishitsuji (ORCID: https://orcid.org/0000-0003-3056-8310)
- Makoto Fujino
- Yoshito IHARA
- Kazuhiko Ino (ORCID: https://orcid.org/0000-0002-6198-0730)
- Uchimura Kenji
- Kaho Nishioka
- Midori Ikezaki (ORCID: https://orcid.org/0000-0003-3629-3629)
- Noa Mori
Institutions
- Centre National de la Recherche Scientifique (FR)
- Wakayama Medical University (JP)
- Unité de Glycobiologie Structurale et Fonctionnelle (FR)
Publication Details
- Journal
- Journal of obstetrics and gynaecology research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1111/jog.70209
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00