Atrial Septal Defect Surgical Closure Following Trametinib Utilization in Noonan Syndrome–Associated Hypertrophic Cardiomyopathy
Infants with severe presentations of NS-HCM and congenital heart defects can be medically stabilized with trametinib and then undergo successful structural heart surgery.
Authors
- Robert J. Dabal
- Grégor Andelfinger (ORCID: https://orcid.org/0000-0002-9047-0502)
- Kristin Linscott
- Camden Hebson
- Sydney Escott
- Guillermo Beltran-Ale
Institutions
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jaccas.2026.107006
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00