Carica Papaya Linn. Leaf Extracts Induced the Proliferation of Mice’s Peritoneal Macrophages and Bone Marrow Cells, Along with Cytokine Modulation in Cell Culture

<i>Carica papaya</i> leaf crude extract and fractions exhibit immunomodulatory effects by promoting cytokine release and peritoneal macrophage and bone marrow cell proliferation, explaining the use of <i>C. papaya</i> in infectious diseases in traditional medicine. Further exploration is needed for applications in immune-related diseases.

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Publication Details

Journal
Journal of Experimental Pharmacology
Published
2026-02-01
DOI
https://doi.org/10.2147/jep.s562891
Primary Topic
Papaya Research and Applications
Type
article
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article

Carica Papaya Linn. Leaf Extracts Induced the Proliferation of Mice’s Peritoneal Macrophages and Bone Marrow Cells, Along with Cytokine Modulation in Cell Culture

Wendwaoga Arsène Nikiema, Kongnimissom Apoline Sondo, R A F Kabore, Rasmané Semdé et al.
Journal of Experimental Pharmacology
Papaya Research and Applications
article

Carica Papaya Linn. Leaf Extracts Induced the Proliferation of Mice’s Peritoneal Macrophages and Bone Marrow Cells, Along with Cytokine Modulation in Cell Culture

Wendwaoga Arsène Nikiema, Kongnimissom Apoline Sondo, R A F Kabore, Rasmané Semdé, Boris Honoré Amadou Ouédraogo, Moussa Ouedraogo, Guillaume Sanou, André Da, Harouna Sore
article en

Abstract

<i>Carica papaya</i> leaf crude extract and fractions exhibit immunomodulatory effects by promoting cytokine release and peritoneal macrophage and bone marrow cell proliferation, explaining the use of <i>C. papaya</i> in infectious diseases in traditional medicine. Further exploration is needed for applications in immune-related diseases.

Journal of Experimental PharmacologyVol. Volume 18
Université Joseph Ki-Zerbo (BF), Centre National de Recherche et de Formation sur le Paludisme (BF)
Openalex Percentile: Top 48%
Papaya Research and Applications
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