All-cause mortality and risk factors for death in patients with Clostridioides difficile infections: a prospective multicentre cohort study in six German university hospitals, 2016-2020
Our study provides a comprehensive assessment of all-cause in-hospital mortality among CDI patients in Germany. By identifying robust and easily accessible risk factors for death, our findings support improved risk stratification and may inform targeted management strategies for high-risk patient populations.
Authors
- C. Schneider (ORCID: https://orcid.org/0000-0002-4292-8574)
- Susanne Herold (ORCID: https://orcid.org/0000-0001-6343-0911)
- Sarah V. Walker (ORCID: https://orcid.org/0000-0001-8288-1793)
- Jan Rupp
- David Tobys (ORCID: https://orcid.org/0000-0001-5528-6059)
- Ellen Piepenbrock (ORCID: https://orcid.org/0009-0002-5772-4782)
- Georg Häcker (ORCID: https://orcid.org/0000-0003-1058-5746)
- Anna M. Rohde (ORCID: https://orcid.org/0000-0002-2190-8267)
- Alexander Mischnik (ORCID: https://orcid.org/0000-0003-2326-4132)
- Ariane Dinkelacker
- T Chakraborty
- Evelyn Kramme
- Jane Falgenhauer (ORCID: https://orcid.org/0000-0002-2949-3166)
- Nadja Käding
- Janina Trauth
- Harald Seifert
- Evelina Tacconelli
- Winfried V. Kern
- Peter Silke
- Frank Schwab
- M J G T Vehreschild
- Michael Behnke
- Can Imirzalioglu
- Susanna Proske
- Nathalie Jazmati
- Michael Buhl
- Georg Pilarski
- Hanna Gölz
- Norbert Thoma
- Larissa Ostertag-Künstle
- Florian Hölzl
Institutions
- Goethe University Frankfurt (DE)
- University of Freiburg (DE)
- University of Cologne (DE)
- Justus-Liebig-Universität Gießen (DE)
- University Medical Center Freiburg (DE)
- Humboldt-Universität zu Berlin (DE)
- Nuremberg Hospital (DE)
- Fraunhofer Institute for Translational Medicine and Pharmacology (DE)
- University Hospital Schleswig-Holstein (DE)
- German Center for Infection Research (DE)
- University Children's Hospital Tübingen (DE)
- Universities of Giessen and Marburg Lung Center (DE)
- University Hospital Frankfurt (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- University Hospital Cologne (DE)
- University of Tübingen (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Journal of Hospital Infection
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jhin.2026.02.004
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00