The burden of cancers and their variations across the states of US: the Global Burden of Disease Study 1990–2021

Cancer remains a major public health issue in the U.S. From 1990 to 2021, national cancer mortality and DALY rates decreased, but incidence increased, highlighting geographic, gender, and socioeconomic disparities. The focus should be on the top ten cancers contributing to DALYs, including ung, colorectal, breast, pancreatic, leukemia, prostate, non-Hodgkin lymphoma, brain, esophageal, and liver cancers, while addressing others as resources allow. Understanding shared etiologies is key for effective intervention strategies.