Comprehensive Analysis of Immunomodulatory-Related Genes Reveals MAPK14-Associated Myeloid-Derived Suppressor Cells Infiltration in Pediatric Sepsis
These findings reveal novel immunomodulatory axes in pediatric sepsis, emphasizing the role of MAPK14 and MDSCs. This work provides potential biomarkers and therapeutic targets for improving the clinical management of pediatric sepsis.
Authors
- Jianze Jiang
- Jia Shi (ORCID: https://orcid.org/0000-0002-1938-3705)
- Wei Dai (ORCID: https://orcid.org/0000-0003-1844-784X)
- Jin Ye
Institutions
- Shangrao Normal University (CN)
- Tongren Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/jir.s568261
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00