BK Polyomavirus Genetic Diversity and Evolution in Kidney Transplant Recipients With Viral Nephropathy According to Whole Genome Sequencing
Among KTR with BKPyVN, we show that BKPyV viral populations change over time, with the coexistence of several viral populations in early samples compared to BKPyVN, as a result of both APOBEC-mediated editing and replication-driven diversification within the kidney allograft.
Authors
- Ahmed Amara (ORCID: https://orcid.org/0000-0001-5401-9864)
- Julien Gras
- Kévin Louis (ORCID: https://orcid.org/0000-0003-1766-2548)
- Linda Feghoul (ORCID: https://orcid.org/0000-0002-2628-7949)
- C. Lefaucheur
- Jérôme Verine
- Marie Laure Néré
- Julien Robert
- Marie Noëlle Peraldi
- Constance Delaugerre
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Saint Louis University Hospital (US)
- Paris Cardiovascular Research Center (FR)
- Kidney Associates (US)
- Hôpital Saint-Louis (FR)
- Ekaterinburg Research Institute of Viral Infections (RU)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-02-15
- DOI
- https://doi.org/10.1093/infdis/jiag108
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00