Practical marker-based stratification of early gastric neoplasms in older adults
MUC5AC/p53 immunohistochemistry is highly effective in identifying high-risk lesions. Enteroblastic differentiation is relatively common and is associated with lymphovascular invasion. These findings support the use of targeted immunohistochemistry for accurately diagnosing and managing this vulnerable and understudied age group.
Authors
- Mana Ideyama (ORCID: https://orcid.org/0000-0002-3563-4826)
- Keisuke Nonaka (ORCID: https://orcid.org/0000-0001-9486-3795)
- Hirofumi Rokutan
- Satoshi Ono
- Tomio Arai
- Toshiyuki Ishiwata
- Nobuo Kanazawa
Institutions
- Kyorin University (JP)
- Tokyo Metropolitan Institute of Gerontology (JP)
- Tokyo Metropolitan Geriatric Hospital (JP)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1093/ajcp/aqag002
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00