Epcoritamab Monotherapy as Outpatient Treatment for Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Interim Results From EPCORE NHL-6
CRS and ICANS incidence and severity were consistent with the pivotal EPCORE NHL-1 trial findings. The results support feasibility of outpatient administration and monitoring of epcoritamab in 2L+ DLBCL without mandatory hospitalization for monitoring.
Authors
- Mark Fesler
- Suchitra Sundaram Sundaram
- Sami Ibrahimi (ORCID: https://orcid.org/0000-0002-7538-346X)
- Fernando Vargas Madueno
- Kristin Conte
- Christian Winther Eskelund (ORCID: https://orcid.org/0000-0002-6409-8081)
- Kojo Osei-Bonsu
- Alexander P. Boardman (ORCID: https://orcid.org/0000-0001-7169-9275)
- John Hrom
- Ralph V. Boccia
- Seema Naik
- Thomas Doerr
- Jeff P. Sharman
- Eric H. Lee
- Mitul Gandhi
- Rakhee Vaidya
- J. Erika Haydu
- Christina Y. Lee
- David Andorsky
- Neha Dixit
- Yang Bai
- Adelba Torres Lopez
- Bradley Lash
Institutions
- Atrium Health Wake Forest Baptist (US)
- Lehigh Valley Hospital-Pocono (US)
- Memorial Sloan Kettering Cancer Center (US)
- AbbVie (United States) (US)
- St. Luke's Hospital (US)
- Memorial Healthcare System (US)
- Hattiesburg Clinic (US)
- Stony Brook Medicine (US)
- Auxilio Mutuo Hospital (PR)
- Virginia Cancer Specialists (US)
- Center for Cancers and Blood Disorders (US)
- Rocky Mountain Cancer Centers (US)
- Compassionate Cancer Care (US)
- Willamette Valley Cancer Institute and Research Center (US)
- Forrest General Hospital (US)
- Center for Cancer Research (US)
- Genmab (Denmark) (DK)
- University of Oklahoma Health Sciences Center (US)
- Stony Brook University (US)
- Penn State Milton S. Hershey Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Clinical Lymphoma Myeloma & Leukemia
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.clml.2026.02.006
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Pharmacyclics