Real-World Durability of Aflibercept 8 mg and Faricimab in Initiators Versus Switchers: A Multicenter Retrospective Analysis

In this real-world cohort, initiation of faricimab or aflibercept 8 mg was associated with greater treatment intervals and improved anatomical outcomes compared to eyes that were switched from older anti-VEGF agents. These findings support early initiation of these anti-VEGF therapies and that step-therapy delays may compromise clinical outcomes.

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Publication Details

Journal
Retina
Published
2026-02-18
DOI
https://doi.org/10.1097/iae.0000000000004813
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-World Durability of Aflibercept 8 mg and Faricimab in Initiators Versus Switchers: A Multicenter Retrospective Analysis

Sundeep D.e.v, Trent Tsun-Kang Chiang, Peter J. Belin, Jade Y. Moon et al.
Retina
Retinal Diseases and Treatments
article

Real-World Durability of Aflibercept 8 mg and Faricimab in Initiators Versus Switchers: A Multicenter Retrospective Analysis

Sundeep D.e.v, Trent Tsun-Kang Chiang, Peter J. Belin, Jade Y. Moon, Richard N. Sather
article en

Abstract

In this real-world cohort, initiation of faricimab or aflibercept 8 mg was associated with greater treatment intervals and improved anatomical outcomes compared to eyes that were switched from older anti-VEGF agents. These findings support early initiation of these anti-VEGF therapies and that step-therapy delays may compromise clinical outcomes.

Retina
University of Minnesota (US), California Retina Consultants (US), The Retina Center (US)
Openalex Percentile: Top 50%
Retinal Diseases and Treatments
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