Orthopaedic Surgical Management in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a progressive X-linked neuromuscular disorder characterized by predictable patterns of muscle weakness, contracture formation, spinal deformity, fracture risk, and cardiopulmonary decline. Although advances in medical and gene-targeted therapies have improved survival and delayed functional deterioration, orthopaedic surgery remains a critical component of comprehensive care. This manuscript provides a detailed, stage-based framework for the orthopaedic surgical management of DMD, emphasizing the integration of neuromuscular progression, functional goals, and systemic risk into operative decision-making.

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Publication Details

Journal
Operative Techniques in Orthopaedics
Published
2025-09-01
DOI
https://doi.org/10.1016/j.oto.2026.101211
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
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article

Orthopaedic Surgical Management in Duchenne Muscular Dystrophy

Asahi Murata, Sean Tabaie
Operative Techniques in Orthopaedics
Muscle Physiology and Disorders
article

Orthopaedic Surgical Management in Duchenne Muscular Dystrophy

Asahi Murata, Sean Tabaie
article en

Abstract

Duchenne muscular dystrophy (DMD) is a progressive X-linked neuromuscular disorder characterized by predictable patterns of muscle weakness, contracture formation, spinal deformity, fracture risk, and cardiopulmonary decline. Although advances in medical and gene-targeted therapies have improved survival and delayed functional deterioration, orthopaedic surgery remains a critical component of comprehensive care. This manuscript provides a detailed, stage-based framework for the orthopaedic surgical management of DMD, emphasizing the integration of neuromuscular progression, functional goals, and systemic risk into operative decision-making.

Operative Techniques in OrthopaedicsVol. 35(3)
Nationwide Children's Hospital (US)
Peace, Justice and strong institutions
Openalex Percentile: Top 33%
Muscle Physiology and Disorders
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