Gathering Orthobiologic Real-word Evidence Using Registries and Biorepositories: Proceedings of the American Academy of Orthopaedic Surgeons-Biologic Association Symposium November, 2022

Orthobiologics represents a growing field of potential orthopaedic therapy. However, the current level of evidence supporting or refuting the use of many biologic agents in clinical practice is sparse and of low quality. The American Academy of Orthopaedic Surgeons and members of the Biologic Association recently convened a symposium dedicated to outlining processes with the goal of accumulating real-world evidence in support of the scientific validity and efficacy of orthobiologic agents. The results of this meeting as well as subsequent ongoing work comprise the American Academy of Orthopaedic Surgeons recommendations for the establishment of registries and biorepositories to assess the value of these treatments moving forward.