Opportunities for Pharmacogenetic Testing Among Hospitalized Children With Medical Complexity

PPIs were the most common CPIC level A medications and are metabolized by CYP2C19, making it the most highly implicated gene. PPI-CYP2C19 should be a PGx testing priority.

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Publication Details

Journal
Hospital Pediatrics
Published
2025-03-01
DOI
https://doi.org/10.1542/hpeds.2025-008751
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Opportunities for Pharmacogenetic Testing Among Hospitalized Children With Medical Complexity

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Opportunities for Pharmacogenetic Testing Among Hospitalized Children With Medical Complexity

Addison Donaher, Kathryn Pavia, Abigail Musial, Carter McIntire, Scott Callahan, Sonya Tang Girdwood, Dakota Skinn
article en

Abstract

PPIs were the most common CPIC level A medications and are metabolized by CYP2C19, making it the most highly implicated gene. PPI-CYP2C19 should be a PGx testing priority.

Hospital PediatricsVol. 16(3)
Cincinnati Children's Hospital Medical Center (US), University of Cincinnati Medical Center (US)
Good health and well-being
Openalex Percentile: Top 26%
Pharmacogenetics and Drug Metabolism
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