A case of ameloblastoma with dystrophic calcification in a hemodialyzed patient

Dystrophic calcification is one of the most frequently observed complications in hemodialyzed patients with chronic renal failure.Dystrophic calcification is related to many factors such as hypercalcemia and hyperphosphatemia.It occurs in various organs, and treatment of highly advanced calcified lesions is difficult.We describe a case of dystrophic calcification within an ameloblastoma in a hemodialyzed patient.The patient was a 72-year-old woman.In November 2021, she was referred to our department for detailed evaluation and treatment after a multilocular radiolucent lesion of the left side of the mandible was noted at a nearby dental clinic.The initial CT scan showed a well-defined multifocal low-absorption area with a maximum diameter of 70 mm and numerous internal high-absorption areas.A biopsy was performed in January 2022 under local anesthesia, and the pathological diagnosis was ameloblastoma and calcification.In June, the patient underwent a jawbone tumor excision and curettage under general anesthesia, and numerous calcifications were found within the lesion.Elemental analysis of the calcified material revealed high levels of calcium and phosphorus, consistent with ectopic calcification in dialysis patients.

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Publication Details

Journal
Japanese Journal of Oral & Maxillofacial Surgery
Published
2025-12-20
DOI
https://doi.org/10.5794/jjoms.71.606
Primary Topic
Oral and Maxillofacial Pathology
Type
article
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article

A case of ameloblastoma with dystrophic calcification in a hemodialyzed patient

Shun Sato, Yuta Yanagisawa, S. Nogami, Hiroyuki Kumamoto et al.
Japanese Journal of Oral & Maxillofacial Surgery
Oral and Maxillofacial Pathology
article

A case of ameloblastoma with dystrophic calcification in a hemodialyzed patient

Shun Sato, Yuta Yanagisawa, S. Nogami, Hiroyuki Kumamoto, Yuka Iwamae, Kensuke Yamauchi
article en

Abstract

Dystrophic calcification is one of the most frequently observed complications in hemodialyzed patients with chronic renal failure.Dystrophic calcification is related to many factors such as hypercalcemia and hyperphosphatemia.It occurs in various organs, and treatment of highly advanced calcified lesions is difficult.We describe a case of dystrophic calcification within an ameloblastoma in a hemodialyzed patient.The patient was a 72-year-old woman.In November 2021, she was referred to our department for detailed evaluation and treatment after a multilocular radiolucent lesion of the left side of the mandible was noted at a nearby dental clinic.The initial CT scan showed a well-defined multifocal low-absorption area with a maximum diameter of 70 mm and numerous internal high-absorption areas.A biopsy was performed in January 2022 under local anesthesia, and the pathological diagnosis was ameloblastoma and calcification.In June, the patient underwent a jawbone tumor excision and curettage under general anesthesia, and numerous calcifications were found within the lesion.Elemental analysis of the calcified material revealed high levels of calcium and phosphorus, consistent with ectopic calcification in dialysis patients.

Japanese Journal of Oral & Maxillofacial SurgeryVol. 71(12)
Tohoku University (JP), Saitama Medical University Hospital (JP)
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Openalex Percentile: Top 23%
Oral and Maxillofacial Pathology
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