Trehalose 6-phosphate as master switch for optimizing crop yield and resilience

Crop breeding faces the challenge of balancing yield with resource efficiency and stress tolerance. The key regulatory metabolite trehalose 6-phosphate (T6P) integrates carbon status with growth and stress responses. Manipulating T6P levels through genetic modification or chemical intervention provides a powerful tool to tackle the growing challenges of crop production.

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Publication Details

Journal
Trends in biotechnology
Published
2026-02-01
DOI
https://doi.org/10.1016/j.tibtech.2025.12.029
Primary Topic
Plant nutrient uptake and metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Trehalose 6-phosphate as master switch for optimizing crop yield and resilience

Mark D. Stitt, Yong-Ling Ruan, Chen Yaning, Muhammad Waqas et al.
Trends in biotechnology
Plant nutrient uptake and metabolism
article

Trehalose 6-phosphate as master switch for optimizing crop yield and resilience

Mark D. Stitt, Yong-Ling Ruan, Chen Yaning, Muhammad Waqas, Zi-Ming Ren, Christoph-Martin Geilfus
article en

Abstract

Crop breeding faces the challenge of balancing yield with resource efficiency and stress tolerance. The key regulatory metabolite trehalose 6-phosphate (T6P) integrates carbon status with growth and stress responses. Manipulating T6P levels through genetic modification or chemical intervention provides a powerful tool to tackle the growing challenges of crop production.

Trends in biotechnology
Australian National University (AU), Zhejiang Sci-Tech University (CN), Xinjiang Normal University (CN), Chinese Academy of Sciences (CN), Xinjiang Institute of Ecology and Geography (CN), Max Planck Institute of Molecular Plant Physiology (DE), Hochschule Geisenheim University (DE)
Decent work and economic growth
Openalex Percentile: Top 50%
Plant nutrient uptake and metabolism
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