Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens
MMP13 may promote aggressive behavior in chordoma by degrading growth-inhibitory COL2-rich ECM. These data support MMP13 as a potential unfavorable prognostic marker and therapeutic target in chordoma.
Authors
- Shinobu Noji (ORCID: https://orcid.org/0000-0002-9774-4799)
- Koichi Matsuo (ORCID: https://orcid.org/0000-0002-1490-8955)
- Yukiko Kuroda (ORCID: https://orcid.org/0000-0002-5335-4238)
- Ryota Tamura
- Masahiro Toda
- Yumiko Oishi
- Katsuhiro Kawaai
Institutions
- Keio University (JP)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71662
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Keio University
- Japan Society for the Promotion of Science